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Uridine phosphorylase 1 (UPP1), an enzyme involved in pyrimidine metabolism, has been found to be elevated in H
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38 The p120 conditional knockout (KO) mice die young (within 21 days of their birth) and demonstrate progressive mucosal erosion and terminal bleeding, similar to what is observed in the dominant-negative cadherin mouse model of colitis and associated cancer, as described above
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