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34 Notably, higher diversification of these dimeric DKP alkaloids is observed via introduction of additional functional groups, including hydroxylation and sulfidation at the DKP rings, leading to distinct and large classes of alkaloids such as the epidithiodiketopiperazines, including (+)-11,11′-dideoxyverticillin ( 19 ) 35 and (+)-chaetocin A ( 20 ), 36 that have been reviewed separately