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Adverse Effects The main adverse effects of pramlintide are generally mild to moderate gastrointestinal symptoms, such as nausea, vomiting, and anorexia, which disappear four weeks after drug use
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Impairment of the PINK1/Parkin pathway results in failure to clear damaged mitochondria in a timely manner, and these dysfunctional mitochondria become a sustained source of ROS, further exacerbating the lipid peroxidation burden (84)
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