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The distinct blood metabolomic fingerprint of PD highlighted in this study is also in line with the findings of prior LC/MS 17,18,19,20,21 and NMR-based 22,23 studies and supports the idea that PD represents a multi-system clinical-pathological entity rather than a CNS-centered disease

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Also, it not only decreased the Bax and caspase-3 expression but also increased the level of Bcl-2 expression in α-Mangostin-treated NPCs

while reducing oxidative stress that triggers discolouration