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The immunogenicity of these peptides in patients with CeD depends on their primary structure, which permits a low to medium affinity fit into the antigen binding groove of HLA-DQ2 or HLA–DQ8 that is governed by the direct interaction of the nine amino acid linear core sequence of the gluten peptide and its interaction with the amino acids of the HLA molecule in which it becomes embedded

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Effects of quercetin and rosuvastatin each alone or in combination on cyclophosphamide-induced premature ovarian failure in female albino mice