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Cannabinoids exert their action on the human body by binding to the receptors that make up the endocannabinoid system, namely CB1 and CB2 receptors
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A rat and dog pharmacokinetic study reported an elimination half-life of the parent peptide under 30 minutes with linear kinetics, bioavailability of roughly 14 to 19 percent in rats and 45 to 51 percent in dogs, and excretion primarily via urine and bile with rapid metabolism into fragments
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