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What follows is a brief overview of findings in • MDD —Starting in 1958 with the FDA approval of iproniazid for the treatment of MDD, all antidepressants up until 2019 worked by modulating one or several of the monoamines serotonin, dopamine, and/or norepinephrine

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Among the glutamine transporting moieties present on the membranes of astrocytes (Table 1), two, according to current data (Table 2), have attracted attention in this context