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It is paramount that these probiotics’ efficacy, especially in reducing uremic toxins by modulating the gut microbiota, be further investigated in CKD patients

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It is interesting that the level of the enzyme which is responsible for the removal of oxidized glutathione, γ-glutamyl transpeptidase in the cells is higher, as if the cells attempt to overcome the increased oxidative stress by trying to get rid of oxidized glutathione (Sian et al., 1994)