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Multiple studies have shown that the Notch and transforming growth factor-β1 (TGF-β1)/Smad3 pathways could trigger epithelial-mesenchymal transition (EMT) and extracellular matrix (ECM) accumulation, leading to renal interstitial fibrosis (85)
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Researchers often use techniques like indirect calorimetry to measure fat oxidation rates in experimental models
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