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Overall, ROS in COPD are driven by exogenous oxidative exposure, NOX system activation, and mitochondrial respiratory chain abnormalities, forming a mutually amplifying pathological network during the process of continuous damage
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The sVEGFR1-i13 splice variant regulates a Ξ²1 integrin/VEGFR autocrine loop involved in the progression and the response to anti-angiogenic therapies of squamous cell lung carcinoma
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