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We also observed nominally higher (16%) GSH (DLPFC) in PTSD males compared to females and higher GSH (DLPFC) among PTSD participants with a history of mTBI ( n = 6)
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This process is mechanistically linked to defective mitophagy and impaired intracellular lipid disposal, suggesting that mitochondrial dysfunction is not merely a downstream consequence of OA but an active amplifier of lipid-mediated cartilage degeneration (59, 70)
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