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The reactivation of S-thiolated GST, GPx or G-3PD could only be efficiently achieved by the catalytic function of RHLT and not by simple GSH reduction, even when physiological levels of GSH were used (1–5 mM)
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“Treatment‐Resistant Depression: Definition, Prevalence, Detection, Management, and Investigational Interventions.” World Psychiatry 22: 394–412
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Consider whether an acceptable alternative could meet the same purpose. Avoid allowing a short deadline to erase an essential requirement.
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