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In its regulation on stem cell differentiation, H 2 S is likely to affect neurogenesis by directly regulating Ca 2+ channels 161 , to initiate endothelial progenitor cell function and to enhance the angiogenesis process of wound sites in type 2 diabetic patients 162
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Remarkably, the replacement of lard with fish oil (40% fat J/J) in chronic (6 weeks) high-fat feeding positively affected mitochondrial dynamic behaviour in association with the improvement of insulin resistance in both skeletal muscle and liver in Wistar rats (Lionetti et al., 2013, 2014)
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