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Moreover, COVID-19-induced metabolic reprogramming characterized by enzyme succinylation, mitochondrial dysfunction, and microbial dysbiosis creates a powerful biochemical milieu that is favorable to nephrolithiasis [30,31]
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The abundance of cysteine residues in proteins increases with organism complexity, ranging from ∼0.50% in archaea to ∼2.25% in mammals [38], and is postulated to reflect the evolution of cysteine's signalling and control functions [39,40]
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