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KPV Research Summary KPV was characterized by Marlene Hiltz and James Lipton at UT Southwestern in a 1989 FASEB Journal paper as the minimal C-terminal anti-inflammatory fragment of α-MSH that retained activity in a murine picryl-chloride contact-dermatitis ear-swelling model despite lacking the central HFRW melanocortin-receptor pharmacophore [14]
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