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Ascorbate and iron Ascorbate can both chelate Fe 3+ and readily reduce it to the more soluble Fe 2+ (also Cu 2+ to Cu + ) and there is evidence that it has a pervasive role in Fe uptake, transport, and storage in animals, as well as being a cofactor/chaperone to prevent Fe over-oxidation in 2-ODDs (Lane and Richardson, 2014
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patients are monitored during each intravenous session
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