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(I) Des-γ-carboxy prothrombin (DCP) is secreted from HCC cells and activates c-Met because it contains two structural regions that are similar to HGF (Suzuki et al., 2005
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In an NTP study, nitrobenzene was administered to B6C3F 1 mice (10 per sex per group) by skin painting (in acetone vehicle) at 0, 50, 100, 200, 400 or 800 mg/kg of body weight per day for 13 weeks (NTP, 1983b)
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