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The sustained effects are thought to result from BPC-157’s activation of multiple gene expression pathways within minutes of administration (including genes like Akt1, VEGFR2, eNOS, and numerous growth factors), which then trigger cascading cellular processes that continue independently

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Intramuscular replacement therapy is indicated for patients with: Significant B12 deficiency (thresholds depend on local laboratory reference ranges) Neurological symptoms or signs Pernicious anaemia Malabsorption syndromes The standard UK regimen for patients without neurological involvement involves hydroxocobalamin 1mg intramuscularly three times weekly for two weeks, followed by maintenance injections every 2-3 months (often 3-monthly)