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The NAD biosynthesis inhibitor APO866 has potent antitumor activity against… [PMID: 19196867] Laboratory literature summary: The NAD biosynthesis inhibitor APO866 has potent antitumor activity against hematologic malignancies
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184 But, in a preclinical study on the DMBA-induced rat mammary carcinoma, this enhanced effectiveness of methotrexate was far outweighted by the growth-stimulating effect of 3-day pretreatment with combined insulin/glucose infusions
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