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Conversely, in the AMDD-after group, differential metabolites (e.g., 2-heptyl-3-hydroxy-4-quinolone) and pathway alterations were significantly directed toward amino acid and energy metabolism (including biosynthesis of amino acids, 2-oxocarboxylic acid metabolism, valine, leucine, and isoleucine biosynthesis, butanoate metabolism, and pyruvate metabolism) as well as lipid pathways (including sphingolipid metabolism and glycerophospholipid metabolism) (Appendix 1 for details)
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