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1.2 Adverse Outcome Pathways and Aggregate Exposure Pathways The AOP offers a structured framework to illustrate the underlying biological mechanisms, connecting a molecular initiating event (MIE) through a series of key events (KE) up to the occurrence of an adverse outcome (AO) at the organism or population level (36)
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Keep missing information visible instead of filling it with guesses. Use the table to support judgment rather than replace it.
Consider whether an acceptable alternative could meet the same purpose. Avoid allowing a short deadline to erase an essential requirement.
Use a cropped view when it fully supports your intended point. Keep enough context to avoid misrepresenting the information shown.
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