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Activated protein kinase 2 (GCN2) and integrated stress response (ISR) can induce autophagy, while glutamine can inhibit this process by inhibiting GCN2 activity and ISR (55, 56)
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Incubating the cells just with ERG showed that it was taken up about 100 times more quickly than was tetraethylammonium, leading to the designation of SLC22A4 as ‘the’ ERG transporter (130)
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