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Elevated levels can react with superoxide to produce peroxynitrite, which can subsequently lead to direct DNA damage and mutations ( The observed alterations in key antioxidant molecules, including H 2 S and GSH in the liver and pancreatic tissues, following chronic ethanol exposure may reflect a disruption of the transsulfuration pathway, a metabolic route responsible for generating these molecules from sulfur-containing amino acids such as methionine and cysteine (Sbodio et al., 2018)

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27.Eichenfield DZ, Sprague J, Eichenfield LF