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Decoding immune resistance in MSS CRC: the role of metabolic–immune crosstalk Immune checkpoint inhibitors (ICIs) have demonstrated significant efficacy in patients with microsatellite instability-high (MSI-H) CRC, yet their therapeutic benefit remains limited in the majority of cases, which are microsatellite stable (MSS) [80]
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Because individuals' needs can exceed food intake during particular illness conditions, carnitine is classified as a “conditionally essential” nutrient
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