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1 Participants were assessed at baseline, 28 days, 6 months, and 12 months post-vaccination (3 time points for the control group), with blood samples used to measure binding IgG antibodies, surrogate neutralizing antibodies, and interferon-gamma release assay (IGRA) responses as a proxy for T-cell immunity against the Ancestral strain and Omicron subvariants BA.1, BA.4/5, and JN.1.1 The trial ran from February 2023 through 12-month follow-up visits with the JN.1 infection wave circulating in Australia between November 2023 and June 2024, overlapping the study's 6- and 12-month assessments
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