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Because morphine poorly stimulates endocytosis of phosphorylated and desensitized MOR (whether MOR is associated with arrestin), the desensitized receptors accumulate at the cell surface causing tolerance
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However, it’s essential to remember that individual experiences may vary, and no treatment can guarantee the same results for everyone
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Keep missing information visible instead of filling it with guesses. Use the table to support judgment rather than replace it.
Consider whether an acceptable alternative could meet the same purpose. Avoid allowing a short deadline to erase an essential requirement.
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