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Despite this limitation, spectrophotometric methods remain valuable for the rapid and economical screening of a wide range of plant-derived bioactive compounds
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Based on these observations and despite the need of additional preclinical data to access the efficacy and toxicity of HDACi, several clinical investigations have started by associating HDACi with immunotherapeutics for patients with advanced prostate, renal, or urothelial cell carcinoma (Mazzone et al., 2017)
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