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While anyone can benefit from healthy B12 levels, certain groups are more likely to experience deficiencies and may see greater advantages from supplementation: Vegans and vegetarians: B12 is primarily found in animal products, making supplementation critical for those on plant-based diets

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42 Meanwhile, osteoclasts activate and resorb irregular new bone through the osteoprotegerin/receptor activator of nuclear factor κB (RANK)/RANKL system to balance the resorption and formation of bone