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This duality is further complicated by evidence that impaired autophagy activates NF-κB through sequestosome 1 (SQSTM1/p62) accumulation, which upregulates NNMT, creating a feedback loop that depletes NAD + and intensifies oxidative stress [14]
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Those figures come from community research logs rather than established doses, and no human dosing study exists for this blend or for any compound in it
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