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The results have revealed that BaP exposure reduced DNA methylation pattern in the promoter region of the CYP1A1 gene which accelerate the metabolism of toxins, but it has been noted that GSTP1 showed increased methylation which reduce its expression that is in turn lead to suppression of detoxification ability (Liu et al., 2022a)
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When recombinant human HGF-activator (rh-HGF-activator) was administered via the portal vein, compared with the control group, and the liver regeneration rate in the rh-HGF-activator-treated group was significantly higher (Kaibori et al., 2002)
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