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136 , 137 Several studies have shown that zidovudine (azidothymidine [AZT]) does not effectively penetrate the BBB in rodents, 138 – 140 although this does not appear to be the result of Pgp export
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Therefore, our data suggest that the effects on the remodeling of proteostatic machinery and lipid homeostasis, in response to enhanced tethering, represent a general phenomenon, applicable for other cell types and diseases other than the above-mentioned AD
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