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Indeed, LDHB knockout (Ldhb −/−) significantly reduced the growth of individual tumor nodules over time, as did treatment with 8 Gy IR daily for three consecutive days (Fig
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In combination with TMZ, the PARP inhibitor niraparib enhances immune recognition by upregulating NKG2DL, leading to increased ULBP1/Mult-1 mRNA expression and improved gamma-delta T cell-mediated cytotoxicity in GBM patient-derived xenografts
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