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These results showed that an early event of propyl gallate-induced apoptosis is MAPKs/Nrf-2-mediated GSH depletion, thus indicating that Nrf-2 is one of the first factors that induce cell survival under GSH depletion, which points out to this transcription factor as an attractive target in leukemia but also in other cancers sharing similar molecular mechanisms
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Noradrenaline, oxymetazoline and phorbol myristate acetate induce distinct functional actions and phosphorylation patterns of α1A-adrenergic receptors
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