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1.2 The pathway of ferroptosis 1.2.1 GSH-GPX4 pathway The fundamental cause of ferroptosis is the imbalance of redox balance between oxidant and antioxidant, which is driven by the abnormal expression and activity of various redox enzymes in the process of producing free radicals and lipid oxidation products or detoxification
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It is interesting to note, however, that these regulators can function cooperatively with other transcriptional regulators that respond to related sulfur-containing species
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