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Glutathione is also a precursor of many detoxifying enzymes, including glutathione peroxidase responsible for neutralising waste products from cellular respiration or the process of ‘cell death’ (apoptosis) (5)

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It is also called dermographia, dermatographic urticaria, or skin writing, and tends to get lumped into atopic dermatitis diagnosis.[ref] Cold urticaria (hives or welts due to cold) or cold-dependent dermatographism, another mast cell-related condition, happens when the skin is lightly scratched after being chilled.[ref] Peripheral neuropathy and mast cell activation: Neuropathy causes numbness, pain, pins and needles, and weakness, usually in the hands and feet