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Furthermore, during kefir fermentation, peptides, polysaccharides, polyphenols, amino acids, and other bioactive components with a variety of nutraceutical benefits are generated, along with more than 50 distinct fragrance compounds (121, 122)
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Additionally, elevated IL-6 can cross the BBB or participate in brain inflammatory responses indirectly by stimulating cerebrovascular endothelial cells, disrupting the integrity of the BBB, and allowing more peripheral harmful substances to enter the brain [46], thereby exacerbating the pathological changes in the brain of PD patients
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