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A more prudent strategy involves limiting necroptosis inhibition to the early phase of AECOPD, primarily driven by viral infection or severe oxidative stress, with short-term combined anti-infection and anti-inflammatory treatment to alleviate inflammation and structural damage while avoiding excessive suppression of long-term immune surveillance and host defense (83, 84) ( Figure 3 )

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To support disc health and prevent future herniations, individuals should focus on maintaining good posture, exercising regularly to strengthen core and back muscles, maintaining a healthy weight, and using proper lifting techniques