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Disclosure of interest: Name of author: nothing to disclose Scientific Communications: imaging 01.00 - ACUTE ISCHEMIC STROKE MANAGEMENT - 01.07 - IMAGING - Non acute O - ESOC25-866 [18F]FEPPA-PET/MRI SHOWS CORRELATION OF CHRONIC NEUROINFLAMMATION AT 6 MONTHS AFTER ISCHEMIC STROKE WITH DEGRADATION IN MULTIPLE AND REMOTE WHITE MATTER PATHWAYS Stefan Poirier 1 , Rachel Wagner 2 , Linshan Liu 1 , Pavlo Ohorodnyk 3 , Michael Jurkiewicz 3 , Alexander Thiel 4 , Jonathan Thiessen 5 , Udunna Anazodo 6 , Alexander Khaw 7 1 Lawson Health Research Institute, Lawson Imaging, London, Canada, 2 Queen's University, School of Medicine, Kingston, Canada, 3 Western University, Schulich School of Medicine and Dentistry, Department of Medical Imaging, London, Canada, 4 McGill University, Jewish General Hospital, Department of Neurology and Neurosurgery, Montreal, Canada, 5 CancerCare Manitoba, Department of Medical Physics, Winnipeg, Canada, 6 McGill University, Montreal Neurological Institute, Department of Neurology and Neurosurgery, Montreal, Canada, 7 Western University, Schulich School of Medicine and Dentistry, Department of Clinical Neurological Sciences, London, Canada Background and Aims: The pathophysiological mechanisms linking chronic neuroinflammation, ischemic white matter (WM) injury, and post-stroke cognitive impairment (PSCI) are not well understood