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Oncology, 49(4), 73-77

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Stable isotope tracing analysis identifies glutamine as the main fuel for the energetic processes of MEC-1/N M and CLL/N M cells To investigate whether enhanced mitochondrial metabolism observed in MEC-1/N M was primarily fueled by glucose or glutamine, we performed stable isotope tracing on MEC-1/N WT and MEC-1/N M cells cultured for 24 h with plate-bound αIgM in media containing either [U- 13 C]-glucose or [U- 13 C]-glutamine (Fig