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GHK as such functions as a complex with Cu 2+ , stimulating both production and destruction of collagen and glycosaminoglycans and also influences metalloproteinases and its inhibitors, promoting skin repair and healing
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Since the reactivity of glutathione (GSH) itself with proteins, small molecules, and xenobiotics is too low to be significant in vivo, see for instance, [2], GSH-dependent reactions need to be catalyzed by enzymes
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