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The phase II trial investigating the addition of the anti-HGF antibody rilotumumab to ECX (epirubicin, cisplatin and capecitabine) chemotherapy in gastric adenocarcinoma demonstrated a modest improvement in progression-free survival (PFS, 5.7 vs 4.2 months) and objective response rate (ORR, 39% vs 21%) [86] compared to placebo plus ECX
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