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MedlineWeb of Science Kalyoncu U, Buyukasik Y, Akdogan A, Karadag O, Bilgen SA, Kiraz S, et al
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The maintenance frequency approach offers middle ground where users completing intensive initial treatment (6-12 months daily) transition to reduced frequency (2-4 times weekly) maintaining copper supplementation at lower intensity and cost while avoiding complete discontinuation allowing some benefit decline
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