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High levels of PUFAs are located in the outer photoreceptor segment and produce substantial amounts of intracellular ROS, making the retina especially susceptible to damage from oxidative stress (166) ( Figure 3 )
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[00252] In some embodiments, in compounds of Formula (II), each R 9 is independently selected from: -C 1 -C 6 alkyl and โ(C 1 -C 6 alkyl)-aryl
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