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EC heterogeneity revealed by scRNA-seq In addition to the well-known EndMT state of ECs, scRNA-seq has significantly advanced the understanding of EC heterogeneity in atherosclerosis by providing detailed insights into the diverse cellular phenotypes and functions within atherosclerotic lesions [22,102]
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Such a cooperative repressive effect on 5XUAS-tk-luc was not observed when Myc-Zfp423 was cotransfected with a Gal4 DNA-binding domain alone expression vector, which we found to slightly decrease luciferase activity (Extended Data Fig
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