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Newly synthesized proteins targeted to lysosomes can be transported either directly into the lysosome through the trans-Golgi network depending on receptors, including mannose-6-phosphate receptor, sortilin, and lysosomal integral membrane protein type 2 87,88 , or indirectly ingested into the lumen by endocytosis 89
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Consider whether an acceptable alternative could meet the same purpose. Avoid allowing a short deadline to erase an essential requirement.
Use a cropped view when it fully supports your intended point. Keep enough context to avoid misrepresenting the information shown.