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The GCase hydrolyses glucoceramide to glucose and ceramide in the lysosome and, thus, plays a role in sphingolipid metabolism (Gegg et al., 2022)
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Further experiments have demonstrated that the peptide is capable of suppressing the activity of pro-inflammatory and fibrotic factors characteristic of the senescence-associated secretory phenotype (SASP), thereby contributing to the restoration of damaged tissue microenvironments
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