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Prolonged α-KG supplementation has exhibited favorable outcomes on insulin sensitivity in obese rats through the augmentation of nitric oxide production in endothelial cells and the inhibition of hepatic gluconeogenesis via diverse pathways 110,135 , which may explain how glucose intolerance is improved in A-T mice after α-KG supplementation
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[DOI] [PubMed] [Google Scholar] 30.Premont RT, Inglese J, Lefkowitz RJ
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