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Basal levels of pro-inflammatory cytokines are elevated in zinc deficiency, but production is ablated upon stimulation (61)
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In response to oxidative stress, NRF2 dissociates from KEAP1 and translocates into the nucleus, where it promotes the transcription of antioxidant and cytoprotective genes, including SLC7A11 , GPX4 , HO-1 , etc
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