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This indicated that the TrxR1/Gsr-null livers excrete much more oxidized GSSG than do wild type livers, which likely is critical for sustaining the reduced state of the intracellular [GSH/GSSG] redox couple in the absence of GSSG-reductase activity [107]
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Autoimmune conditions In certain autoimmune diseases, an accelerated rate of eryptosis can lead to a reduced count of circulating RBCs, consequently resulting in anemia
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