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These smart therapies could be designed to be self-regulating, transforming the challenge of therapy resistance into a new opportunity for targeted cell killing and representing the ultimate convergence of immunology, metabolism, and bioengineering ( Bridging the gap between simplistic 2D cell culture and the immense complexity of an in vivo tumor requires the development and application of more physiologically relevant preclinical models
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doi: 10.1016/j.alit.2016.12.001 41 BerinMCLozano-OjalvoDAgasheCBakerMGBirdJANowak-WegrzynA
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Keep missing information visible instead of filling it with guesses. Use the table to support judgment rather than replace it.
Consider whether an acceptable alternative could meet the same purpose. Avoid allowing a short deadline to erase an essential requirement.
Use a cropped view when it fully supports your intended point. Keep enough context to avoid misrepresenting the information shown.
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